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Dantrolene inhibits release of Ca2+ from the sarcoplasmic reticulum (SR) via inhibition of ryanodine receptor (RYR) channels. Displays selectivity for RYR1 and RYR3 over RYR2.
Protective against the effects of a variety of conditions and agents, including excitatory amino acids. Skeletal muscle relaxant and neuroprotectant.
C14H9N4NaO5
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