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*Please inquire the availability for this product. PC-766B is a 16-membered macrolide antibiotic produced by Nocardia brasiliensis, reported by researchers at Sumitomo in 1993. Structurally, PC-766B is a member of bafilomycin class, featuring a rare butadiene side-chain. PC-766B is active against Gram positive bacteria, and some fungi and yeasts, but is inactive against Gram negative bacteria. It shows activity against murine tumor cells in vitro and in vivo, and weak inhibitory activity against Na/K-ATPase in vitro.

Additional Information

Product #	P-2747
CAS #	108375-77-5
Formula	C43H68O12
MW	777
Appearance	Light orange solid
Purity	>95% by HPLC
Solubility	Soluble in ethanol, methanol, DMF or DMSO
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	An antibiotic with activity against gram positive bacteria and some fungi and yeasts

Additional Information

InChI	InChI=1S/C43H68O12/c1-12-13-14-17-33-28(6)36(53-37-22-32(44)40(47)31(9)52-37)23-43(49,55-33)30(8)39(46)29(7)41-34(50-10)18-15-16-24(2)19-26(4)38(45)27(5)20-25(3)21-35(51-11)42(48)54-41/h12-18,20-21,26-34,36-41,44-47,49H,19,22-23H2,1-11H3/b13-12+,17-14+,18-15-,24-16-,25-20-,35-21-/t26-,27+,28+,29?,30-,31+,32+,33+,34-,36+,37+,38-,39+,40+,41+,43+/m0/s1
SMILES	C/C=C/C=C/[C@@H]1[C@H]([C@@H](C[C@@](O1)([C@@H](C)[C@@H](C(C)[C@@H]2[C@H](/C=C\C=C(/C[C@@H]([C@@H]([C@@H](/C=C(\C=C(\C(=O)O2)/OC)/C)C)O)C)\C)OC)O)O)O[C@@H]3C[C@H]([C@@H]([C@H](O3)C)O)O)C