The antibody detects endogenous levels of total F2RL2 protein.
Applications:
IHC
Reactivity:
Human
Immunogen:
Synthetic peptide corresponding to a region derived from internal residues of human coagulation factor II (thrombin) receptor-like 2
Host:
Rabbit
Clonality:
Polyclonal
Conjugate:
Unconjugated
Purification:
Antigen affinity purification.
Concentration:
2mg / ml
Formulation:
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:
Store at -20?C
Target
Function:
Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
Tissue Specificity:
Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.
Sequence Similarities:
Belongs to the G-protein coupled receptor 1 family.
Post-Translational Modification:
A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.